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Cannabis Education

An in-depth look at the study that discovered THCP, a cannabinoid more potent than THC

A new cannabinoid has been discovered, and the ramifications could be massive. Scientists funded by the UNIHEMP research project have discovered a new psychoactive molecule: Δ9-Tetrahydrocannabiphorol, or THCP; and they believe that there are great scientific implications for the phytocannabinoid

Phytocannabinoids are cannabinoid molecules that are specifically produced by plants. There are several types of cannabinoids, including endocannabinoids, synthetic cannabinoids, and phytocannabinoids. 

Endocannabinoids are compounds that are produced within the body by an organism’s endocannabinoid system; and synthetic cannabinoids are man-made chemicals that cannot be found in nature. Phytocannabinoids, on the other hand, are a different beast altogether. They are those that naturally occur in plants and are found in a variety, including echinacea. However, the plant species in which phytocannabinoids are most prominent is cannabis.

Because of cannabis’ status as a Schedule I controlled substance in the US, there are several barriers that prohibit the scientific study of the plant and its constituents. Thus, a considerable portion of cannabis research takes place abroad. Many clinical and laboratory studies of cannabis take place in Israel and Canada, where there is federal research funding to support this work; but, the newly discovered THCP was characterized by a group of Italian scientists.

Unlike the US, government funding for cannabis research is relatively commonplace in Europe. The discovery of THCP was enabled by the UNIHEMP project, which is sponsored by the European Regional Development Fund. A multi-disciplinary team of Italian scientists was responsible for the discovery of this novel cannabinoid, led by Giuseppe Cannazza of the University of Modena and Reggio Emilia.

The researchers’ findings were published in late 2019 in the journal Nature.

THCP is 33-times more active than THC

Throughout the duration of the project, the group studied a medicinal cannabis cultivar, dubbed FM2, which was supplied by the Military Chemical Pharmaceutical Institute in Florence. Using a variety of scientific characterization techniques, the researchers observed two novel cannabinoids, THCP and CBDP, and isolated them from other cannabinoids that were present. Following this discovery, the group artificially synthesized THCP and CBDP to create reference materials, and the synthesized versions were successfully used to verify the natural expression of the two cannabinoids in the FM2 cultivar.     

After the confirmation of the identity of the two cannabinoids, the group turned its focus to THCP. To study the compound, they pursued an in vitro experiment with cultured cells. This experiment tested the binding affinity of THCP with CB1 and CB2 receptors, using synthetic cannabinoids as reference materials. It was shown that, when comparing THCP-related results to the previously reported data of other cannabinoids against the CB1 receptor, THCP is 33-times more active than delta-9 THC. 

This finding is critical because the group also found that the chemical was present in FM2 at 0.0029%, whereas THC was found to be expressed at 3.9%; so, even in smaller amounts, THCP is more active than THC.

They also tested the cannabimimetic activity of the molecule. Cannabimimetic activity is a measure of how well a substance replicates the effects of more well-characterized cannabinoids which bind to the CB1receptor. An in vivo experiment involving mice was performed. Herein, the influence of THCP on body temperature, spontaneous activity, immobility, and pain was determined — the results of these tests confirmed that THCP acts similarly to other cannabinoids like delta-9 THC.

Will THCP be important?

According to the study, even at lower doses, THCP has more cannabimimetic activity than THC. Further, the group posits that THCP could account for the wide variability of patient responses in cannabis-based therapies, even amongst cultivars with equal THC doses. This means  that cannabis’  psychotropic effects, which the scientific community attributes to THC, may actually be due to the presence of THCP. 

Unfortunately, none of the original researchers could be reached for comment. However, experts in the field do have varying opinions regarding the study. Dr. Cecilia J. Hillard of the Medical College of Wisconsin said, “I think it is well designed.” She goes on, “[The study] has two important gaps, in my opinion. First, they should have compared the in vivo effects of THCP to that of THC ‘head to head’ so that relative potencies could be assessed. Second, I would like to know whether THCP has greater efficacy to activate the [CB1 receptor] in particular. THC is relatively safe because it has low efficacy at the receptor. If THCP has high efficacy (like the synthetic analogs that have also increased the tail length), it is a more concerning finding, as it would suggest that strains making a lot of THCP could be more dangerous to use than those that do not.” 

Expanding on how THCP could be more dangerous, Hillard continued, “The so-called ‘spice’ compounds are synthetic agonists of the CB1 receptor. They are full agonists, meaning that they are very strong activators of the CB1 receptor. Compared to THC, these drugs have significant adverse effects and produce significant dependence (addiction). So, my issue is that we do not know yet whether THCP is like THC, a partial agonist, or like the synthetic compounds, a full agonist. And my concern is that, if it is the latter, cannabis strains high in THCP will have more adverse effects than those that are low.”

Dr. Samuel Banister of The University of Sydney states, “[The study] was well designed and executed,” concurring with Dr. Hillard. However, he goes on to disagree with the group’s assessment that THCP may account for the variability of psychotropic effects across various cannabis cultivars: “While this possibility cannot be ruled out, the known potency differences for THC and THCP at cannabinoid receptors is relatively small, while the difference in abundance of each in cannabis is enormous. The same is true of CBD and CBDP, although CBD requires even higher doses to achieve many of its pharmacological effects. For this reason, I do not feel that minor or trace phytocannabinoids like THCP or CBDP contribute significantly to the psychoactive effects of different cannabis strains.” 

How this novel cannabinoid plays out in both medical and recreational use is yet to be determined, as much more research is needed. Nonetheless, this new evidence suggests that analytical laboratories in US regulated markets may need to expand their testing panel to include THCP.

Featured graphic by David Lozada/Weedmaps



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Cannabis Education Videos

How to Make Cannabis Rice – Easy THC Rice – Cannabis Edibles



Learn how to make infused rice with our easy recipe 🌿. This recipe involves a rice cooker, but, if you use a pot to cook rice it will work too. Feel free to ask questions in the comment section below.

How to make cannabis coconut oil in a mason jar: https://youtu.be/M3_cwt4lKuE

How to make cannabis coconut oil in the oven: https://youtu.be/_NTiA80GlG8

How to decarboxylate cannabis (easiest method): https://youtu.be/ijJFJZZ5-ts

Mason Jar decarboxylation: https://youtu.be/RTP99pKLx7o

Learning how to cook with cannabis is an empowering experience for any cannabis consumer whether medical or recreattional.

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Cannabis Training Videos

How Does THC University Work? – Training for the cannabis industry



For aspiring cannabis entrepreneurs, THC University’s online classes are a great option if you’re looking to learn everything you need to know about weed. http://bit.ly/31Jzwac

More Cannabis Education: I Love Growing Marijuana http://bit.ly/2N9jOB7

Download Growing Elite Marijuana EBook http://bit.ly/2TCjnRf

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Cannabis Education: The benefits and success stories of THC & CBD



Thank you to @RxMaryJade for visiting The Lorri Love Show and providing us several answers to common questions surrounding the uses and benefits of CBD and THC.
In this episode @RxMaryJade helps us understand what the difference is between CBD and THC and how each one serves its own purpose and has provided real life results as alternative medicines. She also gives us key pointers on how to spot real CBD products versus the fake ones that are sold online. @RxMaryJade also covers how to obtain a medical marijuana card and several other topics.

RXMaryJade is a Cannabis Educator who has spoken at hundreds of forums and seminars to educate others and answer questions surrounding cannabis, its several benefits, and how certain products can help with certain health conditions. She shares how her own life story is a testimony to the benefits of the natural plant and also shares the stories of others. She does provide her own links to products she has tried and finds to be of high quality on her website and recommends that anyone with additional questions reach out to her.

The Lorri Love Show supports @RxMaryJade and believes that everyone should check out what she is doing, go to one of her events, and try her homemade CBD products.

Thank you to live4beats.net for providing the theme music to the show !

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How to Prepare for Drug Tests and Get THC Out of Your System

Pursuing a new job can be both an exciting and nerve-wracking experience, but for cannabis users or anyone considering using cannabis, it can also induce the gut-wrenching fear of an unexpected drug test followed by a frantic search for quick ways to do a marijuana cleanse.

Even in states with medical or adult-use cannabis legalization in full swing, some jobs still maintain stringent drug policies that forbid employees from consuming cannabis on their own time.

Having advance notice of an upcoming drug test may give you enough time to take a tolerance break and abstain from consuming, regardless it’s important to understand how THC operates throughout the body and how to healthily and effectively move cannabinoids out of your system.

How Does THC Move Through the Body?

You might have heard rumors that cannabis can stay in your system for days, weeks, or maybe even months, but the way THC travels and interacts with the body paints a slightly more complex picture.

If cannabis is smoked or vaporized, THC enters the bloodstream from the lungs and goes directly to the heart, where it is then pumped throughout the body to the two types of cannabinoid receptors found in the human body.

“THC travels in the blood to the CB1 receptors located in the brain and central nervous system, and the CB2 receptors located in the spleen and immune system,” said Itzhak Kurerk, Ph.D., CEO and co-founder of Cannformatics, a Northern California biotech company researching improvements to medical cannabis.

THC molecules binding to the cannabinoid receptor.

Every time the blood circulates throughout the body, a certain portion of THC passes through the liver. When THC is broken down in the liver, it forms at least 80 different metabolites, including 11-hydroxy-THC (11-OH-THC) and 11-nor-9-carboxy-THC (THC-COOH), both of which are inactive forms of THC that remain in the body far longer than active THC. Some of these metabolites, such as THC-COOH, are stored in body fat and gradually eliminated from the body through urine and feces.

“Tests for cannabis consumption mainly detect a metabolite of THC found in urine,” Kurek explained. “This metabolite [THC-COOH] is a result of the detoxification process in the liver by cytochrome P450 enzymes and further oxidation.”

When cannabis is ingested in the form of an edible or capsule, THC enters the bloodstream through the walls of the stomach and intestine. THC will travel directly to the liver where a substantial amount is eliminated or metabolized before the cannabinoid receptors are activated. After that, the remaining THC and its corresponding metabolites are put into circulation by the heart, where they both reach the brain.

So, contrary to what some might think, most cannabis drug tests aren’t only specifically looking for THC, but also metabolites such as THC-COOH that are created as the cannabinoid is rapidly broken down in the body.

Types of Drug Tests

Currently, there are drug screening methods designed to detect the presence of THC and THC metabolites in urine, blood, saliva, and hair.

Urine

A urine test is the preferred method used to screen for cannabis use, as this is the recommended test by the Substance Abuse and Mental Health Services Administration (SAMHSA), a branch of the U.S Department of Health and Human Services that creates drug testing standards for government employees.

A 2012 study published in the Iranian Journal of Psychiatry explained why urine tests are more effective than blood, saliva, or hair. “Urine is the preferred sample because of higher concentration and longer detection time of metabolites in it. Moreover, urine can easily be sampled,” the study stated.

Urine drug tests have a specific sensitivity regarding the cutoff concentration of THC-COOH, the benchmark used to determine the results of the test. While the cutoff point can generally range from 15 nanograms per milliliter (ng/mL) to 100ng/mL, the most common cutoff used for urine tests is 50 ng/mL, which is the value recommended by SAMHSA. This cutoff concentration determines the timeframe that a drug test will show up positive or negative for cannabis use. To fully grasp the finite scope of this cutoff limit measurement, consider that a nanogram is one-billionth of a gram, while a milliliter measures fluid volume equal to 1/1,000 of a liter. In the case of a marijuana drug screening, the test results would be positive if the amount of THC metabolites in the sample exceeded 50 ng/mL.

Blood

The researchers from the same 2012 study also stated that blood tests can only detect cannabis use a few hours after consumption.

“Maximum delta-9-THC plasma concentration was observed approximately 8 minutes after onset of smoking, while 11-OH-THC peaked at 15 minutes and THC-COOH at 81 minutes. This delta-9-THC concentration rapidly decreases to 1-4 ng/mL within 3-4 hours,” the study stated.

Saliva

Cannabis use can also be detected in saliva, but this also has a more limited window. A 2014 review on cannabinoids in oral fluid found that THC could be detected in occasional users one to three days after use, while saliva in chronic users could be detected up to 29 days after use.

Hair

Hair tests are the most sensitive type of drug tests, and can detect THC and THC-COOH up to 90 days after consumption. But these tests have proven to be inaccurate, and even non-consumers could trigger a false positive if they come into contact with a cannabis user. A 2015 study published in Scientific Reports, bluntly titled “Finding cannabinoids in hair does not prove cannabis consumption,” stated: “At first glance, differentiation of the route of THC-COOH incorporation into hair seems irrelevant as long as positive THC-COOH findings in hair require THC uptake by the individual under investigation. However, considering the presence of THC-COOH in sebum/sweat, a transfer to other persons’ hair is possible.”

How Long Does it Take for THC to Move Out of Your System?

As for the question of how long THC can be detected in your system, it depends not only on the type of drug tests, but also relies on a variety of individual factors, such as the consumer’s metabolism and amount of cannabis used.  

“How long cannabis stays in your system is still an open question, and depends on many factors,” Kurek explained. “Experiments on frequent cannabis users have found residual THC can be detected for 5-13 days post-consumption.”

There are a variety of factors that might impact the amount of time that THC will stay in your system, including:

    • Dosage: The greater the amount of THC, the longer it will take the body to detoxify and excrete THC and its metabolites.
    • Frequency of use: How much and for how long does a  consumer use marijuana?
    • Genetics: People inherit different variants of the cytochrome P450 superfamily of enzymes, which modify THC in the body resulting in excretion in the urine, according to Kurek.
    • Sex: Some studies have shown that men who smoke marijuana may have higher circulating levels of THC than women.
    • Weight: The more body fat the cannabis user has, more THC metabolites are stored in the body and for longer periods.
    • Metabolism: What’s the rate at which the body can eliminate the presence of cannabis from the system?

Although we’ve established that there’s no clear cut answer on how long it takes to get THC out of your system, past research on THC detection methods allows us to estimate the time it takes to cleanse the body of marijuana.

A 2005 review by Paul Cary, director of the Toxicology and Drug Monitoring Laboratory at the University of Missouri, found that while detection times in excess of 30 days do occur in some cases, they are largely an exception. The study acknowledges the various factors that determine how long THC metabolites remain in the body, but also provides “practical cannabinoid detection guidance” to offer a general idea of how long marijuana will stay in an individual’s system.  

“Based upon recent scientific evidence, at the 50 ng/mL cutoff concentration for the detection of cannabinoids in urine (using the currently available laboratory-based screening methods) it would be unlikely for a chronic user to produce a positive urine drug test result for longer than 10 days after the last smoking episode,” the study stated.  

At a lower 20 ng/mL cutoff concentration, the study also states that it would be uncommon for a chronic marijuana smoker to produce a positive urine drug test result longer than 21 days after consumption. For those who only use cannabis occasionally, the review states that it would be unusual for cannabinoids to be detected in urine three to four days after consumption at the 50 ng/mL cutoff level. For one-time marijuana use, the most stringent 20 ng/mL cutoff concentration point shouldn’t detect cannabinoids after 7 days.

Using a specified cutoff concentration point and time frame, drug testing laboratories are essentially able to look at levels of THC metabolites and figure out the last time the subject used cannabis.

“If the lab quantitates how much THC-11-hydroxy or THC-11-carboxy is found, that can be used to date when your last use of THC was, approximately,” explained Dr. Joseph Morgan, Senior Medical Director at Onconova Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing small-molecule drug candidates to treat cancer.

“In other words, somebody who tests for no THC, no 11-hydroxy-THC, and a small amount of 11-carboxy-THC [THC-COOH], they can reliably say they were not stoned at the time of the test, and most likely their most recent use was at least a week before, possibly even one or 2 months before,” he added.

While these guidances help construct a framework for the court system and employers to follow, random drug screenings have a tendency of catching cannabis users by surprise. In the event you have a surprise drug test coming up and you’re unsure whether you still have THC in your system, it’s possible to give your body a marijuana cleanse that is legal and healthy.  

Easy, Ethical Ways to Do a Marijuana Cleanse

It might be hard to admit, but the most effective way to give your body a marijuana cleanse is simple: Don’t consume any cannabis for one to three months. If abstaining from THC is not an option for you, know that because the most common type of drug test is a urine screening, the terms “marijuana cleanse” or “detox” typically refer to cleaning THC metabolites out of urine until they’re undetectable.  

First, don’t try to cheat a drug screening under any circumstances, especially not by purchasing fake urine or other strange products that could get you into trouble,” Morgan warns of the risk of using products that supply fake chemical urine. “If you’re found doing that, then they’ll know you’re obviously guilty of something,” he said.

There are plenty of detox products that claim to assist with a marijuana cleanse, but keep in mind that these detox methods may not be 100% effective. One popular way to detoxify the body is by using bentonite clay, a clay made from volcanic ash that is purported to absorb toxicants, chemicals, and other impurities from the body. It can be used internally by mixing some into a glass of water.

Outside of detox formulas, there are other effective practices you can integrate into your daily routine. Focus on things like physical health, vitamin and food intake, while also recognizing how THC metabolites enter the urine. Morgan added an important caveat, explaining that exercising a day or two before a drug screening could cause THC-COOH to be released from fat cells into the urine stream.

“Try to be healthy and not fat, be well-hydrated, but don’t exercise vigorously the day before or the day of your drug test,” Morgan explained.



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U.S. Government Marijuana Has So Little THC, It’s Closer to Hemp

Research-grade marijuana that’s supplied by the only federally authorized cultivation site in the United States is genetically closer to hemp than cannabis varieties sold at dispensaries in legal states, according to a new study.

The revelation raises questions about how applicable the results of research using the government’s marijuana really are to understanding the effects of products that consumers are actually using.

Previous studies have demonstrated that marijuana that’s grown at the University of Mississippi, with funding from the National Institutes On Drug Abuse (NIDA), has lower levels of THC and cannabidiol (CBD) compared with commercial cannabis products. But researchers at the University of Northern Colorado wanted to learn specifically about their genetic variance.

The study, which was made available as a preprint on bioRxiv, looked at 49 cannabis samples, including hemp and NIDA-supplied marijuana, as well as various indica, sativa and hybrid strains sold in the commercial market. When the samples were genetically analyzed, the researchers were surprised to find just how different NIDA’s marijuana is from the cannabis most people are consuming.

As has already been established, marijuana and hemp proved to be genetically distinct. But interestingly, research-grade cannabis from NIDA shared a closer “genetic affinity with hemp samples in most analyses” than with commercially available marijuana, the study authors wrote.

via bioRxio.

“Our genetic investigation adds to this previous research, indicating that the genetic makeup of NIDA Cannabis is also distinctive from commercially available medical and recreational Cannabis,” they wrote. “To our knowledge, this is the first genetic study to include research-grade marijuana from NIDA, and its placement with hemp samples was unexpected.”

The findings raise concerns about the results of federally approved marijuana research that has relied on the NIDA supply. If the research concerned individual components of cannabis such as THC and CBD, the samples might be useful, but study participants who consume the NIDA varieties may be experiencing different effects than patients and consumers that get their marijuana from dispensaries.

“As the interest for medical Cannabis increases, it is important that research examining the threats and benefits of Cannabis use accurately reflect the experiences of the general public,” the researchers wrote.

U.S. Government medical marijuana crop at the University of Mississippi in Oxford, Mississippi

Advocates, scientists, and lawmakers have already been urging the Justice Department to expand the number of federally authorized marijuana manufacturing facilities, arguing that the limited supply and diversity of cannabis varieties available from the government’s current sole source is hindering research, but the approval process has been slow-moving.

Whether it will speed up under new Attorney General William Barr is yet to be determined, but he has voiced support for such expansion and said in January 2019 that he would “review the matter and take appropriate steps.

 

This article has been republished from Marijuana Moment under a content syndication agreement. Read the original article here.



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Cannabis Education Videos

Whats is the difference between THC and CBD – Cannabis Educational video – Cannapiece Group



Cannabis plants have been found to have over 100 cannabinoids, groups of active compounds found in marijuana that produce many of the effects you feel from using the plant. So far, no cannabinoids are more popular than THC and CBD.
What makes these two compounds so different and why?

Tetrahydrocannabinol, or THC, and Cannabidiol, or CBD, are the most well known compounds in cannabis for the potential effects they can produce

In recent years, a high CBD strain also known as Charlotte’s Web, has gained attention around the globe. It is named after Charlotte Figi, a girl who suffers from a rare form of epilepsy called Dravet syndrome

Charlotte was treated when she was 5 years old with the strain and it had outstanding effects, greatly reducing her seizures

So why is it that CBD can have these effects, and THC doesn’t?

THC and CBD are made up of the same molecules.

Cannabinoids act on cannabinoid receptors in cells that alter neurotransmitter release in the brain, which explains why they affect so many different body functions

However, THC has the ability to get you high, and CBD does not. WHy is this?
THC is a psychoactive compound that produces the euphoric effect of cannabis

CBD has shown on the other hand that it may actually inhibit thc’s ability to get you high and may actually decrease this affect

CBD is currently being studied for it’s antispasmodic, anti nausea and anti-inflammatory effects

The atoms in THC and CBD are actually quite different, explaining why the two have such different effects on the body

This aspect makes an immense difference in how it affects our bodies

THC works by easily binding to CB1 receptors in your brain, therefore producing the euphoric effect and feelings of being high

Some people want the potential benefits of cannabis without getting high from it, making CBD an increasing attractive option. CBD doesn’t bind to CB1 receptors easily, therefore inhibiting the ability to get you high.

A new drug “Epidiolex” was released and approved by the FDA in 2018. It is an oral CBD solution that has shown to treat Lennox Gastaut syndrome, and Dravet syndrome- both two rare forms of epilepsy.

This was a moment that went down in history. This was the first time that the FDA has ever approved of a drug substance derived from cannabis. It is also the first time that a drug has been found and approved to treat Dravet syndrome.

So, is the role of THC no longer important? Not entirely.

Studies have shown that THC can help CBD have the effects that it does.

When taken orally, only about 6% of CBD oil is absorbed.

THC actually enhances the benefits of CBD and makes it easier for the body to absorb, making this duo quite the pair when taken together.

Studies show that CBD can potentially treat: psychosis, seizures, anxiety, depression, nausea, Pain, inflammation, mental disorders, and migraines

While THC has been studied to potentially treat: pain, glaucoma, insomnia, low appetite, anxiety, Muscle spasticity, Nausea, and also enhance mood

Both THC and CBD differ by having their own potential individual benefits and effects on our systems, however finding the best combination of cannabinoids for your own unique body could be the key.

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Thank you for watching our video based on cannabis information and cannabis education about the laws around Cannabis in Canada issued by health Canada and government of Canada about the cannabis industry in Canada.

Our effort is to educate and help anyone interested to learn more about Cannabis and cannabis industry especial the micro grower and micro grow cultivators in the cannabis field for medical cannabis.

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THC UNIVERSITY | ONLINE TRAINING FOR THE CANNABIS INDUSTRY | THC UNIVERSITY REVIEW



Register as a student & enroll in courses
Once enrolled as a student you can enroll in certification programs and start learning immediately. You also get access to M-F student support, monthly webinars, and grow support.

Enroll Now: http://soo.gd/vUEv

Learn at your own pace
Every student has 24/7 access to courses so you can learn at your own pace from anywhere in the world. We’ve also partnered with industry experts, like Jorge Cervantes, to bring you high quality courses that you won’t find anywhere else.

Take quizzes and get certified
Take quizzes to put your knowledge to the test and prove that you’re one of the top candidates in the industry. Once you pass the final exam we’ll send you a certificate of completion and you’ll get access to our exclusive student jobs board.

Get Certified Now! Go Here: http://soo.gd/vUEv

Start your new career
We’ve created the world’s largest cannabis jobs board exclusively for THCU certified students. Plus, graduates get a free resume and interview consultation.

Start Immediately: http://soo.gd/vUEv

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THC vs CBD: What's In Your Weed?



How do CBD and THC work differently?
Two Stoned Guys Try To Explain The Respiratory System | STONED SCIENCE: https://youtu.be/Pz0g5VA3pF0

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References / Further Reading:

https://blogs.plos.org/scicomm/2018/07/05/cbd-is-certainly-a-big-deal/
https://www.kcl.ac.uk/ioppn/news/records/2018/august/cannabis-extract-helps-reset-brain-function-in-psychosis.aspx
https://www.kcl.ac.uk/ioppn/news/records/2017/12-December/cannabidiol-cbd-could-represent-a-‘new-class-of-treatment’-for-psychosis.aspx
https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2697762
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852356/
https://www.ncbi.nlm.nih.gov/pubmed/18656454
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852356/#cam41312-bib-0004
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189631/
https://www.ncbi.nlm.nih.gov/books/NBK425755/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120766/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436336/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820295/
https://arizonamedicalmarijuanaclinic.com/cbd-vs-thc-why-is-cbd-not-psychoactive/
https://www.analyticalcannabis.com/articles/cbd-vs-thc-what-are-the-main-differences-297486
https://www.reuters.com/article/us-health-cannabis-psychosis/cannabis-ingredient-holds-promise-as-antipsychotic-medicine-idUSKBN1E90P6
https://ajp.psychiatryonline.org/doi/abs/10.1176/appi.ajp.2017.17030325
https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2697762

Tags: Science, AsapSCIENCE, Whiteboard, CBD, THC, CBD vs THC, THC vs CBD, THC and CBD, Medical Marijuana, Weed, Hemp, Cannabis, Legalize Weed, Weed in Canada, Stoned Science, Joint, Vaping, Vaping vs Smoking, Pot, CBD for Seizures, Is CBD Good for You, Benefits of, Education, CBD as Medicine, Why Does Weed Make You High, Cannabidiol, Smoking, Is Weed Good For You, Marijuana, CBD Anti-Anxiety, CBD Chronic Pain, Drug

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THC Design : Budtender Training Program



Our goal is to help educate Budtenders about THC Design, our mission and cannabis products in general to help them be more knowledgable the next time a customer walks through the door. Being informed is a huge part of being able to make quality cannabis recommendations for customers and patients alike.

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